Board Thread:General Discussion/@comment-24979796-20140527195418/@comment-24386552-20140728164348

He cared for Izzie especially. When George died, he was devastated but more focused on her. The woman who left him for a heart patient. S6, their relationship sucked because of all the crap that was happening. Izzie also failed to understand that it wasn't Alex's fault for her being fired. Something she told him in 6.09 and said she couldn't forgive him. He couldn't forgive her for her abandoning him, assuming he got her fired, and on top of that left him with a 200,000 medical bill. In 6.12, they worked out their issues, but ultimately their relationship was gone by then. Plus the actress who played Izzie had issues of her own, causing the "Bad writing" she mentioned when refusing to accept an Emmy.