How to Save a Life

"OPENING VOICEOVER"

- Meredith Grey

 is the twenty-first episode of the eleventh season and the 241st overall episode of Grey's Anatomy.

Short Summary
Derek witnesses a horrible car accident and springs into action to save lives.

Main Cast

 * Ellen Pompeo as Dr. Meredith Grey
 * Justin Chambers as Dr. Alex Karev (credit only)
 * Chandra Wilson as Dr. Miranda Bailey
 * James Pickens, Jr. as Dr. Richard Webber (credit only)
 * Sara Ramírez as Dr. Callie Torres (credit only)
 * Kevin McKidd as Dr. Owen Hunt (credit only)
 * Jessica Capshaw as Dr. Arizona Robbins (credit only)
 * Sarah Drew as Dr. April Kepner
 * Jesse Williams as Dr. Jackson Avery (credit only)
 * Caterina Scorsone as Dr. Amelia Shepherd
 * Camilla Luddington as Dr. Jo Wilson
 * Jerrika Hinton as Dr. Stephanie Edwards (credit only)
 * Kelly McCreary as Dr. Maggie Pierce (credit only)
 * Patrick Dempsey as Dr. Derek Shepherd

Guest Stars

 * Larry Cedar as Dr. Cohn
 * Mike McColl as Paul
 * Samantha Sloyan as Edie
 * Allie Grant as Alana
 * Savannah Paige Rae as Winnie
 * Che Landon as Sarah

Co-Starring

 * Robby Rasmussen as Charlie Abbott
 * Scott Rinker as Toby
 * John Eddins as Firefighter
 * Thomas Owen as Police Officer
 * Jennifer Aquino as Anesthesiologist
 * Irene Park as Paramedic #1
 * Joe Raffa as OR Nurse

Patient

 * Diagnosis:


 * Doctors:


 * Treatment:

Notes and Trivia

 * This episode's title originated from the song , originally sung by The Fray. The song was featured on the episode Superstition and was also sung by Kevin McKidd, Ellen Pompeo, Kim Raver, Eric Dane, Jessica Capshaw, Chandra Wilson, Chyler Leigh, Sarah Drew, Justin Chambers, and Sara Ramírez during the musical episode Song Beneath the Song.
 * This episode scored million viewers.
 * Filming for this episode was scheduled from March 20 to March 31, 2015, but the filming continued for an extra day, thus ending on April 1, 2015.
 * This episode will feature action scenes which were filmed in Griffith Park.
 * This is the first episode with Shonda Rhimes as the credited writer since Flight, the season eight finale.