Brian Williams

Brian Williams is the father of Rory Williams, a patient at Grey Sloan Memorial Hospital.

Cancer
His wife’s family has a history of repeated cancer, which manifested in his daughter, Rory.

Rory’s Cancer
Rory had brain cancer at age ten which was fully cured. However, when Rory was sixteen, she was diagnosed with osteosarcoma and was also discovered to have a tumor in her chest.

Li-Fraumeni
Rory having three cancers by age sixteen and the family history of prominent cancer diagnoses prompted Miranda Bailey to look for a genetic reason. She discovered a mutation of the P53 gene and concluded that the family carried Li-Fraumeni Syndrome, which affects their bodies’ ability to regulate cell growth.

Rory’s Death
Rory became unresponsive and wasn’t breathing properly, so she was rushed into surgery. Despite the doctors’ best efforts, Rory bled out into her chest and died. When the doctors came to tell the Williams family, they were distraught and it prompted Ariel to ask the doctors if she also had Li-Fraumeni, which she did.

Patricia Williams
Brian is married to Patricia Williams, with whom he has two daughters, Rory and Ariel.