Board Thread:General Discussion/@comment-26372051-20150528101405/@comment-4287993-20150625174317

They could just offer us an update on her career/life. She could have started a family and one of her children or her husband could suffer from a severe medical condition for which they need the best surgeons (who you can find at GSMH, or so we're always shown/told). Or Izzie could have become a professional herself and she can be flown in to help out on a difficult case, like Lauren Boswell. There are a lot of options to bring her back.