Penelope Blake

Penelope Blake is a surgical resident at Grey Sloan Memorial Hospital. Previously, she was a resident Dillard Medical Center, prior to its closure, who treated Derek Shepherd after his car accident. She is currently in a relationship with Callie Torres.

Childhood
As a child, Penny moved every two years due to her mother's job. ("Guess Who's Coming to Dinner")

She hated high school, which she attributes to cheerleaders. ("All Eyez on Me")

Derek's Death
Penny was one of the doctors who tended to Derek Shepherd when he came into the Dillard ER. She put in his chest tube and his thoughts indicated that he liked her, said she was smart. She wanted to order a head CT, but Paul insisted that they didn't have time and they needed to take him into surgery to get his abdominal bleeding under control.

While they were on the way to the OR, she made one final play to get the CT, since he was stable. Paul again declined and they took Derek into surgery and started operating. When he became unstable, Paul finally remembered that he'd had a head laceration and had the anesthesiologist check his eyes, which revealed a blown right pupil. They paged the neurosurgeon, Dr. Cohn, who said he'd be there in 20 minutes because he was at a dinner. Despite this, it took him an hour and a half to arrive. Penny called him out on this and he responded that they should have gotten a head CT and they would have paged him sooner. When she continued to say that he should have gotten there faster because Derek might have had a chance if he had, he kicked her out of the OR.

She went with Dr. Cohn to speak to Meredith about Derek's death and Meredith told them that the decision not to get a CT was a bad decision.

When Meredith exited the hospital, Penny was on a bench outside crying. She went up to Meredith to apologize again, but Meredith told her that Derek was her one, the patient whose face she'll see every time she treats a patient. He'll haunt her and remind her that he died on her watch. It'll either make her a better doctor or she'll quit and Meredith says she doesn't get to spend what would have been the rest of Derek's life being a quitter and then sends her back inside because she's not saving any lives outside. ("How to Save a Life")

Dinner Party
Long after Derek's death, Penny began seeing Callie Torres. They dated for a while and Callie invited Penny to come to a dinner party at Meredith's with her. She and Meredith were both shocked to see each other when Callie and Penny arrived at the party. ("Old Time Rock and Roll")

Penny tried repeatedly to get Callie to let them leave the party, but Callie, thinking it was just nerves about meeting Arizona and her other friends, insisted that Penny stay, even when Callie herself got called to the hospital. Meredith kept quiet about the connection to Penny, but it came out when Penny was asked about why she was transferring to Grey Sloan Memorial Hospital. The doctors were all shocked by the news and Penny left the house. Later, after coming back in to use the bathroom, Penny met up with Meredith, who had come back downstairs after going up to hide in her bedroom. Penny said she'd ask for a transfer so they wouldn't have to work together, but Meredith told her that she'd see her on Monday and not to be late. ("Guess Who's Coming to Dinner")

First Day at Grey Sloan Memorial
On her first day at GSM, Penny was assigned to Meredith Grey's service. She helped Meredith treat Robert Matthews, but Meredith critiqued her every step of the way and eventually kicked her off her service. However, after speaking to Richard, Meredith agreed to give Penny another chance and asked for her on her service for the rest of the week. ("The Me Nobody Knows")

Work with Meredith
Meredith continued to have Penny on her service, running her ragged. Penny eventually confronted Meredith, saying that she could hate her, but she hadn't let Penny quit, so she shouldn't quit either. And if Meredith wasn't going to teach her, she should let her go. Meredith later let her help with a kidney transplant. ("Something Against You")

Meredith's Attack
Penny found Meredith after she was attacked by Lou. She helped treat her initial injuries and then followed her recovery. When Meredith had a panic attack after a visit with her kids didn't go well, Penny cut the wires holding the broken jaw together. Jackson yelled at her for it, but she defended that Meredith needed air and her jaw could be re-wired the next morning. ("The Sound of Silence")

Meeting Sofia
When Sofia came into the ER, Penny was given the case because of her relationship with Callie. However, she hadn't yet met Sofia. When Callie found out that Penny had treated Sofia without paging her, she claimed that Arizona wasn't comfortable with Penny meeting Sofia yet. Penny immediately went to Arizona to apologize, but Arizona said that she had no part in it and Callie had lied. Penny believed it was because she'd told Callie she loved her the previous night. Callie later told Penny they were on the same page and invited her to get ice cream with her and Sofia. ("When It Hurts So Bad")

Preminger Grant
When the opportunity came up for Penny to apply for the Preminger Grant, she initially decided she didn't want to because she believed she didn't have a chance at it. However, she ultimately decided to apply. She had support of several attendings and was given the grant, which funded a year of residential research at the Preminger Research Center. ("I Wear the Face")

Callie Torres
Penny is dating Callie Torres. She was not aware of Callie's friendship with Meredith Grey until Callie brought her to a dinner party at Meredith's House. ("Old Time Rock and Roll")

After the dinner party, they didn't speak for a few days because Penny thought Callie was taking Meredith's side, though Callie said she was on both sides. However, after Penny's first day at Grey Sloan Memorial, they both agreed they were in it. ("The Me Nobody Knows")

Penny constantly being on Meredith's service upset Callie, which strained their relationship. ("Things We Lost in the Fire")

They broke up briefly, but they met in a stairwell at work and Callie admitted to Penny that she missed her and Penny kissed her. ("All I Want is You")

One night, as they were in bed getting ready to sleep, Penny told Callie she loved her. Callie replied, "Thank you." The next day, after Penny treated Sofia, Callie told her that she was on the same page and she'd been there for a while, but she had a history of being on that page too early in the past, which is why she was hesitant. ("When It Hurts So Bad")

Familial
Her mother is a petroleum seismologist, so they moved every two years.

Friendships
After starting work at Grey Sloan Memorial Hospital, Penny began to bond with the other residents, particularly Stephanie Edwards, Jo Wilson, and Ben Warren.

Paul
Paul, one of her co-workers, seemed to have little respect for her. Over her objections, he refused to take Derek for the head CT that might have saved his life. Derek's thoughts said that Paul didn't like Penny because she was smarter than him, even though she's younger, and probably because she's a woman. ("How to Save a Life")

Amelia Shepherd
When Penny was hired to work at GSM, Amelia refused to work with her. However, they were forced to work together when Richard Webber scrambled the attending/resident pairs. After seeing Penny work on Griffin McColl, Amelia admitted that she was a born neurosurgeon, which meant Amelia would have to start teaching her. ("Odd Man Out")

Career
Penny was a surgical resident at Dillard Medical Center. However, when Dillard closed, she was re-matched to Grey Sloan Memorial Hospital to continue her residency. She's currently in her third year.

Notes and Trivia

 * Although her name was not mentioned in How to Save a Life, closed captioning and subtitles displayed her name as Edie, however, she was re-introduced in Old Time Rock and Roll as Callie's girlfriend named Penny.
 * She was in college before she ever tried macaroni and cheese. ("Guess Who's Coming to Dinner")
 * She liked physics. ("My Next Life")