With a Wonder and a Wild Desire

"OPENING VOICEOVER"

- Meredith Grey

 is the first episode of the fifteenth season and the 318th overall episode of Grey's Anatomy.

Main Cast

 * Ellen Pompeo as Dr. Meredith Grey
 * Justin Chambers as Dr. Alex Karev
 * Chandra Wilson as Dr. Miranda Bailey
 * James Pickens, Jr. as Dr. Richard Webber
 * Kevin McKidd as Dr. Owen Hunt
 * Jesse Williams as Dr. Jackson Avery
 * Caterina Scorsone as Dr. Amelia Shepherd
 * Camilla Luddington as Dr. Jo Karev
 * Kelly McCreary as Dr. Maggie Pierce
 * Giacomo Gianniotti as Dr. Andrew DeLuca
 * Kim Raver as Dr. Teddy Altman

Guest Stars

 * Greg Germann as Dr. Thomas Koracick

Patient

 * Diagnosis:


 * Doctors:


 * Treatment:

Notes and Trivia

 * This episode's title originated from the song , originally sung by Flogging Molly.
 * This episode scored million viewers.