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Susan Grey was the second wife of Thatcher Grey (Meredith Grey's father), she has two children named Lexie and Molly.

She is Meredith Grey's stepmother. Meredith often refers to her as her "surrogate mother." Susan was always aware of Thatcher's first wife and daughter, and had reached out to Meredith, offering to include her in their family and encouraging her to develop a relationship with Thatcher.

At first, Meredith was resistant to Susan's desire to mother her, claiming she already had a mother but when Ellis Grey died, Meredith was reached out to again. Meredith grudgingly accepted it and as a result, the two bonded and became friendly.


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