Board Thread:General Discussion/@comment-24479404-20140128215444/@comment-5278765-20140129002834

Seattle is the 22nd most populous city in the US, part of the 15th most populous metropolitain area, and it's on the rise. Areas of similar size would be Detroit and Minneapolis/St. Paul (which is where Cristina went at the start of season nine). Boston is much larger than Seattle and Indianapolis much smaller. However, Boston does have a top ranked teaching hospital (and Meredith lived there with her mother as a child). I think Boston would be a much more likely setting for a show similar to Grey's Anatomy than Indianapolis.