Dr. A. Knox is an attending anesthesiologist at Grey Sloan Memorial Hospital.


Meredith's First Solo SurgeryEdit

When Meredith performed her first solo surgery, a colectomy, Dr. Knox was her anesthesiologist. ("What a Difference a Day Makes")

George's DeathEdit

Dr. Knox was the anesthesiologist for the surgery in which George became brain dead. ("Good Mourning")

Randy HelsbyEdit

When Randy Helsby had surgery to try to remove his cancer, Dr. Knox was his anesthesiologist. ("Tainted Obligation")

Hospital ShootingEdit

After Derek was shot by Gary Clark, Knox was the anesthesiologist who worked on the surgery when Cristina operated on him. ("Death and All His Friends")

Owen and Cristina's House HuntEdit

When Cristina and Owen were looking for a house after they married, Dr. Knox mentioned during surgery that his sister was looking to sell her house. ("Can't Fight Biology")

Drew McNeilEdit

When Drew McNeil needed surgery, Knox was on the surgical team. When Alex asked if Drew was under, Knox said that he was. ("Slow Night, So Long")

Jason PaizEdit

When Jason Paiz was rushed to the OR after falling 100 feet into a ravine, Knox was in the surgery. ("Adrift and at Peace")

Bailey's SurgeryEdit

When Bailey was operating and live-tweeting, Knox was in the surgery. He helped keep the patient stable while she took the pancreas to Tacoma Methodist to get islet cells to help the patient. ("Don't Deceive Me (Please Don't Go)")

Oliver RichterEdit

When Oliver Richter was rushed into emergency surgery, Knox was the anesthesiologist on the case. ("Golden Hour")

Henry's Heart MassEdit

When Henry Burton had a mass near his heart, Knox was on his surgery. ("This is How We Do It")

Callie's AccidentEdit

After Callie and Arizona were in a car accident while Callie was pregnant, Knox was the anesthesiologist who worked on her. He was scolded when her anesthesia was too light and she was awake as they prepared to operate. ("Song Beneath the Song")

Ed BeckertEdit

Ed Beckert was in surgery to have his probe injected for Derek's Alzheimer's trial, but they were all shocked when he had a heart attack and died before they could even get started. ("It's a Long Way Back")

Carl ShatlerEdit

When Carl Shatler was hit by a car after falling off a truck, Dr. Knox was his anesthesiologist. When his pressure tanked, Dr. Knox admitted he didn't know why. ("Put Me In, Coach")

Conjoined TwinsEdit

When Andi and Brandi Evans were scheduled to be separated, Ben Warren traded with Dr. Knox so Dr. Knox worked on Andi and Brandi while Ben took another case. ("This Magic Moment")

Thomas PetersonEdit

When Thomas Peterson had a tumor resection, Dr. Knox was his anesthesiologist. During his surgery, Dr. Knox informed them his fontanelle was bulging and his pupils were dilated. ("One Step Too Far")

Holly WheelerEdit

When Holly Wheeler was found in the woods and brought to the hospital, Dr. Knox was her anesthesiologist. He told the doctors when he was ready to put Holly under. ("The Girl with No Name")

Graham CunninghamEdit

When Bailey operated on Graham Cunningham, Dr. Knox was the anesthesiologist. He informed them when Graham's lactate level went from 9 to 17 rapidly. ("I Was Made for Lovin' You")

Leon KeltonEdit

Dr. Knox was on the surgical team of Leon Kelton, who was impaled by several metal bars after the wind caused him to fall at a construction site. There was some danger of explosion as the sparks of the grinding metal could combust the oxygen in the OR, but the doctors come up with a relatively safe plan to cut the bars. ("Readiness is All")

Lenny ShulteEdit

When Lenny Shulte had surgery, Dr. Knox was the anesthesiologist. Knox informed them when he started having arrhythmias and went into PEA. After 20 minutes of CPR, Dr. Knox said his pH was down to 7.1. ("Seal Our Fate")

Mickey WenschlerEdit

When Mickey Wenschler had surgery, Derek asked Dr. Knox to turn up his heart monitor. His heart rate was erratic and his BP was rising. Derek checked his reflexes and Knox informed him that there was no brain activity. ("Map of You")

Travis ReedEdit

When Travis Reed has his hips replaced, Dr. Knox was on the surgery. After they prepared to close, Knox said that he was having trouble ventilating. They had to close quickly. ("Sorry Seems to Be the Hardest Word")

Adult Conjoined TwinsEdit

When Annie and Liz Cooper were separated as adult, Knox was their anesthesiologist. When they were separated and Annie was moved to another OR, Knox stayed with Liz. ("We Are Never Ever Getting Back Together")

Steve TateEdit

When Steve Tate had emergency surgery, Knox was his anesthesiologist. Knox informed them that Steve's pupils were fixed and dilated and he had no gag reflex. ("Got to Be Real")

Emily JensenEdit

When Emily Jensen needed a c-section to deliver her baby at 28 weeks, Knox was her anesthesiologist. When she started bleeding heavily, Graham Maddox told Arizona she'd gone through two or three units of blood and Knox corrected that she'd actually had eight. ("Could We Start Again, Please?")


When Micah needed surgery after falling off a ski lift, Dr. Knox was his anesthesiologist. He informed the doctors he'd gone through four units of blood. ("I Feel the Earth Move")


When Tess fell while rock climbing, Dr. Knox was her anesthesiologist. When she became unstable, he checked her pupils and said they were dilated and non-responsive. ("I Am Not Waiting Anymore")

Gretchen McKayEdit

When Gretchen McKay needed surgery after an emergency c-section in the hallway, Knox was her anesthesiologist. ("There's a Fine, Fine Line")

Cynthia DanielsEdit

When Cynthia Daniels was donating a kidney to her son, she became unstable when they went to close. Knox informed them there was no history of high blood pressure to help explain it. ("Back Where You Belong")

Max SpencerEdit

Dr. Knox worked on the surgery when Max Spencer had a Ladd's procedure. ("Break Down the House")

Tyler RichardsonEdit

When Tyler crashed during surgery, Knox checked him and helped determine he was having an allergic reaction. ("You Really Got a Hold on Me")


When Nisha needed debridement due to flesh-eating bacteria, Dr. Knox was part of the team that went into the hyperbaric chamber with her. After she was declared dead, he was stuck in the chamber while they waited for it to decompress. ("Broken Together")

Phoebe MossEdit

Dr. Knox worked on Phoebe Moss's surgery. When her brain herniated, he checked her pupils and found no response, indicating brain death. ("Blowin' in the Wind")

Claire ConwayEdit

Dr. Knox was the anesthesiologist for Claire Conway's surgery. When the surgery abruptly became urgent, he worked to sedate her quickly. Instead of sedating her, he accidentally injected the sedative into Owen's IV, which he had connected due to influenza. After that mistake, he apologized and went on to sedate Claire. ("Help, I'm Alive")

Shirley GregoryEdit

Dr. Knox worked on the surgery of Shirley Gregory, who had liver tumors. When there was a complication, he kept them updated on Shirley's condition. ("Reunited")

Paul CastelloEdit

Dr. Knox worked on the case of Paul Castello, who had a brain hemorrhage. ("My Shot")

Taryn HelmEdit

Knox did anesthesia for Taryn Helm, who had surgery to repair her leg and then to repair internal bleeding. ("Help Me Through the Night")

Chuck ThompsonEdit

Knox was the anesthesiologist for Chuck Thompson. ("A Hard Pill to Swallow")

Suzanne BritlandEdit

Knox was on the case when Suzanne Britland had a pericardial window. He welcomed Maggie back, causing Suzanne to worry how long Maggie had been away and if she was rusty. ("Save the Last Dance for Me")

Guthrie HamiltonEdit

Dr. Knox was the anesthesiologist for Guthrie's surgery. When Guthrie started crashing, he announced it to the OR. ("Sing It Again")



Dr. Knox has a sister, whose house was located near Meredith's House. At some point in her life, she wanted to sell the house. Dr. Knox and Derek suggested that Cristina and Owen buy it, as they were looking for their own house, but they decided to buy the firehouse instead. ("Can't Fight Biology")


Dr. A. Knox is an anesthesiologist at Grey Sloan Memorial Hospital.

Notes and TriviaEdit

  • There is also a season one character named Dr. Knox.
  • He was mentioned in Perfect Storm when Derek said that he was on standby in case Meredith needed drugs to help her through giving birth.



Episode StillsEdit


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