Grey's Anatomy Seasons
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The sixteenth season of Grey's Anatomy will premiere September 26, 2019 on ABC.



Showrunner Krista Vernoff confirmed the season would chronicle following storylines:

  • The ramifications of Meredith, Richard, and Alex's being fired and Meredith going to jail.
  • The continuing love triangle between Owen, Teddy, and Tom.
  • Amelia taking time to figure out who she is.
  • Jo's emergence from her psychiatric treatment.


Main Cast

Recurring Guest Stars

Prominent Guest Stars

Recurring Co-Stars

Notes and Trivia

  • The renewal for the show's sixteenth season was first somewhat confirmed on February 5, 2019. Karey Burke, President of ABC Entertainment, stated at a TCA session that the show was implicitly renewed for its sixteenth season when Ellen signed on for seasons 15 and 16. At the same time, she confirmed that they were in early conversations to keep Grey's going even beyond the sixteenth season. This renewal was made official on May 10, 2019.
  • Production for this season started on July 15, 2019.
  • The table read for the season premiere took place on July 25, 2019.
  • A kick-off party for cast and crew took place on July 28, 2019.
  • Ellen Pompeo and Giacomo Gianniotti filmed their first scene on July 29, 2019.
  • The show will see the development of a romance between a character from Grey's and one from Station 19. Additionally, with Krista Vernoff now helming both shows, the worlds will blend more together. While ABC's entertainment president Karey Burke had previously stated that there would be "weekly cross-overs", she later re-iterated that statement and said that there will likely be only 3 to 4 real cross-over events peppered throughout the season.[1]
  • On August 8, 2019, TVLine announced that Krista Vernoff had informed them that she was trying to get a former main cast member back for an appearance this season, but she didn't share who it was or for how many episodes.[2]


No. in series No. in season Title Directed by Written by Original air date
343 1 "16.01" September 26, 2019
344 2 "16.02" Kevin McKidd October 3, 2019
345 3 "16.03" October 10, 2019
346 4 "16.05" October 17, 2019
347 5 "16.05" October 24, 2019
348 6 "16.06" October 31, 2019
349 7 "16.07" November 7, 2019
350 8 "16.08" November 14, 2019


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  • On August 6, 2019, filming took place at Masters University and a nearby location. The scenes include no loud noises or special effects.


DVD Release


Cast Promotional Photos



  1. TVLineGrey's/Station 19: New Inter-Show Romance Eyed — Plus: ABC Boss Walks Back 'Weekly Crossover' Comment
  2. TVLineGrey's Anatomy Alum Being Eyed for Season 16 Return — But Which One?
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