Grey's Anatomy Universe Wiki
Grey's Anatomy Universe Wiki
Grey's Anatomy Seasons
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

The eighteenth season of Grey's Anatomy was announced on May 10, 2021. It will air on Thursday nights at 9/8c starting September 30, 2021. As of now, the season has not been designated as the final season of the series. Krista Vernoff will continue to serve as showrunner on both Grey's Anatomy and Station 19.[1]




Main Cast

Special Guest Stars

Recurring Guest Stars

Prominent Guest Stars

Recurring Co-Stars

Notes and Trivia

Easter Egg Hunt

Ellen Pompeo had the idea to sprinkle Easter eggs referencing back to the history of the show throughout the episodes of the season. The following section bundles all the Easter eggs sorted by episode.

18.01 - Here Comes the Sun

  • The close-up of Meredith's face when she awakens from her dream is reminiscent of the close-up shown in A Hard Day's Night when she wakes up on the living room floor after her one-night stand with Derek.
  • The white striped shirt and beige pants she wears throughout the episode is very similar to her outfit worn on her first day at Seattle Grace.
  • David tells Meredith she is the spitting image of her mother. Richard told her the exact same thing in the first episode.
  • Meredith tells Nick she is not sleeping with him, which she also told Derek in The First Cut Is the Deepest.
  • The room in the background of Ellis's appearance in Meredith's dream is where she first appeared in the pilot, Roseridge Home for Extended Care.
  • The Minnesota Mayo Clinic was previously featured in early season 9 when Cristina worked there. The location fits with previous statements that Ellis Grey worked there (as well as Nick Marsh).

18.02 - Some Kind of Tomorrow

  • TBA


No. in series No. in season Title Directed by Written by Original air date
381 1 "Here Comes the Sun" Debbie Allen Meg Marinis September 30, 2021
As the city of Seattle revels at the Phoenix Fair celebrating the city's rebirth post-COVID, the Grey Sloan doctors treat a patient who encounters illegal fireworks. Meanwhile, Bailey has her sights set on hiring new doctors, but she's having trouble finding viable options. Owen and Teddy attempt to take the next step in their engagement, and Meredith has a surprising opportunity when she meets a dynamic doctor from her mother's past.
382 2 "Some Kind of Tomorrow" Kevin McKidd Felicia Pride October 7, 2021
Meredith seeks advice from Amelia. Meanwhile, Richard is reenergized as he takes teaching to a new level at the hospital, and Winston treats a patient suffering from kidney failure.
383 3 "Hotter Than Hell" Chandra Wilson Jamie Denbo October 14, 2021
Seattle's favorite redhead returns and graces the Grey Sloan halls with her experience and expertise as she attempts to help Richard teach the newest crop of residents. Meanwhile, Meredith has a decision to make, and Link confides in Teddy.
384 4 "With a Little Help From My Friends" October 21, 2021
Richard recruits Meredith and Bailey to help him launch a new program. Meanwhile, Addison's patient has complications from a procedure, and Jo helps a woman who goes into premature labor.
385 5 "Bottle Up and Explode!" November 11, 2021
386 6 "Everyday Is a Holiday (With You)" November 18, 2021
387 7 "18.07" November 25, 2021
388 8 "18.08" 2021
389 9 "18.09"



DVD Release


TV Guide's Kate Walsh Return Photoshoot


  1. 1.0 1.1 ‘Grey’s Anatomy’ Renewed For Season 18 With Ellen Pompeo, Chandra Wilson & James Pickens Jr. Set To Return; ‘Station 19’ Picked Up For Season 5 By ABC
  2. Greg Germann Exits ‘Grey’s Anatomy’ As Series Regular