Grey's Anatomy Universe Wiki
Grey's Anatomy Seasons
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The eighteenth season of Grey's Anatomy was announced on May 10, 2021. It will air on Thursday nights at 9/8c starting September 30, 2021. Krista Vernoff will continue to serve as showrunner on both Grey's Anatomy and Station 19.[2]




Main Cast

Special Guest Stars

Recurring Guest Stars

Prominent Guest Stars

Recurring Co-Stars

Notes and Trivia

  • The series was officially renewed for season eighteen on May 10, 2021.[2]
  • All three remaining originals - Ellen Pompeo, Chandra Wilson, and James Pickens, Jr. - signed new contracts for the season as their contracts expired at the end of season seventeen. Jesse Williams' contract also expired but he opted to leave the series near the end of the previous season. As such, it will be the first season since season six not to feature Dr. Jackson Avery as a series regular.
  • Filming for the season started on August 11, 2021.
  • The promotional poster for the season includes Miranda Bailey and Richard Webber. The last time the poster featured other characters besides Meredith Grey was season fourteen, which featured all remaining originals at the time.
  • T.R. Knight has been shadowing directors this season.
  • Due to COVID-19, the holiday break was extended. Instead of resuming production on January 10, 2022, it was pushed back to January 12, 2022.
  • This is the first season since season six to feature a two-hour finale.

Easter Egg Hunt

Ellen Pompeo had the idea to sprinkle Easter eggs referencing back to the history of the show throughout the episodes of the season. The following section bundles all the Easter eggs sorted by episode.

18.01 - Here Comes the Sun

  • The close-up of Meredith's face when she awakens from her dream is reminiscent of the close-up shown in A Hard Day's Night when she wakes up on the living room floor after her one-night stand with Derek.
  • The white striped shirt and beige pants she wears throughout the episode is very similar to her outfit worn on her first day at Seattle Grace.
  • David tells Meredith she is the spitting image of her mother. Richard told her the exact same thing in the first episode.
  • Meredith tells Nick she is not sleeping with him, which she also told Derek in The First Cut Is the Deepest.
  • The room in the background of Ellis's appearance in Meredith's dream is where she first appeared in the pilot, Roseridge Home for Extended Care.
  • The Minnesota Mayo Clinic was previously featured in early season 9 when Cristina worked there. The location fits with previous statements that Ellis Grey worked there (as well as Nick Marsh).

18.02 - Some Kind of Tomorrow

  • TBA


No. in series No. in season Title Directed by Written by Original air date
381 1 "Here Comes the Sun" Debbie Allen Meg Marinis September 30, 2021
As the city of Seattle revels at the Phoenix Fair celebrating the city's rebirth post-COVID, the Grey Sloan doctors treat a patient who encounters illegal fireworks. Meanwhile, Bailey has her sights set on hiring new doctors, but she's having trouble finding viable options. Owen and Teddy attempt to take the next step in their engagement, and Meredith has a surprising opportunity when she meets a dynamic doctor from her mother's past.
382 2 "Some Kind of Tomorrow" Kevin McKidd Felicia Pride October 7, 2021
Meredith seeks advice from Amelia. Meanwhile, Richard is reenergized as he takes teaching to a new level at the hospital, and Winston treats a patient suffering from kidney failure.
383 3 "Hotter Than Hell" Chandra Wilson Jamie Denbo October 14, 2021
Seattle's favorite redhead returns and graces the Grey Sloan halls with her experience and expertise as she attempts to help Richard teach the newest crop of residents. Meanwhile, Meredith has a decision to make, and Link confides in Teddy.
384 4 "With a Little Help From My Friends" Michael Watkins Jess Righthand October 21, 2021
Richard recruits Meredith and Bailey to help him launch a new program. Meanwhile, Addison's patient has complications from a procedure, and Jo helps a woman who goes into premature labor.
385 5 "Bottle Up and Explode!" Lindsay Cohen Kiley Donovan & Beto Skubs November 11, 2021
The Grey Sloan doctors spring into action after an explosion rocks Seattle, with the incoming trauma hitting close to home. Owen experiences PTSD after he hears the explosion, while his sister Megan enlists help from Winston and Hayes in confidence. In Minnesota, Meredith and Amelia meet up with a familiar face who assists in their study
386 6 "Everyday Is a Holiday (With You)" Tony Phelan Meg Marinis November 18, 2021
It's Thanksgiving and while Meredith faces travel complications due to the weather, Nick steps in to help in more ways than one. Meanwhile, Richard and Bailey seek out emergency surgeries, and Amelia and Link reconnect.
387 7 "Today Was a Fairytale" Debbie Allen Julie Wong December 9, 2021
Dr. Hamilton takes his frustrations out on Meredith, so Nick gives her a chance to blow off steam by scrubbing in on a surgery. Back in Seattle, Link and Jo take their kids to a fairytale theater performance that goes wrong. Bailey and Dr. Lin attend a recruitment fair in hopes of attracting more doctors to Grey Sloan but find themselves ill-prepared.
388 8 "It Came Upon a Midnight Clear" Michael Watkins Jase Miles-Perez December 16, 2021
The doctors of Grey Sloan Memorial celebrate the holidays. Hamilton and Meredith prepare for a milestone on their project. Link wants to spend the holiday with Amelia and Scout as a family, and Schmitt is faced with a difficult decision during surgery.
389 9 "No Time to Die" Linda Klein Krista Vernoff February 24, 2022
The Grey Sloan Memorial doctors grapple with the aftermath of the car crash that involved some of their own, while Meredith works to save Dr. Hamilton's life. After Levi is severely impacted from his latest loss, Bailey is forced to once again rethink the Webber Method. Later, Link confronts Amelia after witnessing her move on with someone new.
390 10 "Living In a House Divided" Allison Liddi-Brown Jamie Denbo March 3, 2022
Schmitt must face the Morbidity and Mortality conference. Meanwhile, Meredith convinces Nick to scrub in on a surgery in Seattle, and Jo faces her feelings.
391 11 "Legacy" Kevin McKidd Mark Driscoll March 10, 2022
While Meredith, Amelia and the team prepare for Dr. Hamilton's long-awaited, groundbreaking surgery, Bailey receives an unexpected offer. Owen's impatience makes him a difficult physical therapy patient, forcing Link to intervene. In Minnesota, Nick makes a liver transplant a teaching moment.
392 12 "The Makings of You" Debbie Allen Felicia Pride March 17, 2022
Nick whisks Meredith away to his Minnesota cabin for a romantic weekend, leaving Winston and Maggie to care for Meredith's children. Meanwhile, Amelia and Kai grow closer.
393 13 "Put the Squeeze On Me" Allison Liddi-Brown Julie Wong March 24, 2022
While Richard ponders his surgical abilities, Jo is charmed by her patient's brother. Elsewhere, Megan makes sure Teddy and Owen talk out their differences, and a pet python causes an uproar.
394 14 "Road Trippin'" Linda Klein Beto Skubs March 31, 2022
Tensions at Grey Sloan Memorial rise as the effects of the physician shortage begin to show. Meanwhile, Meredith struggles to step away from work as she spends a sick day at home with Zola, and the hospital receives an unexpected visitor.
395 15 "Put It to the Test" Kevin McKidd Zoanne Clack April 7, 2022
Bailey is on edge when an accreditation council stops by Grey Sloan to review the residency program, while Richard sets an assessment of his own for the same day. Meanwhile, Nick returns to Seattle to perform a first-of-its-kind operation with Meredith.
396 16 "Should I Stay or Should I Go" Michael Watkins Jase Miles-Perez & Jess Righthand May 5, 2022
Bailey faces an unhappy Catherine who is facing audits for several of her Foundation hospitals. Meanwhile, Addison is back at Grey Sloan, tensions rise between Meredith and Richard, and Owen returns to work.
397 17 "I'll Cover You" Debbie Allen Emily Culver & Kiley Donovan May 12, 2022
A former patient of Link's, Simon, is in the ER with his pregnant wife and Bailey receives an offer from Nick.
398 18 "Stronger Than Hate" Chandra Wilson Julie Wong May 19, 2022
A dinner party is thrown at the sister house in Nick's honor. Meanwhile, Grey Sloan Memorial receives a victim of a brutal hate crime.
399 19 "Out for Blood" Kevin McKidd Meg Marinis May 26, 2022
Due to a blood shortage, Grey Sloan Memorial is setting up a voluntary donation center. Meanwhile, Nick asks Meredith for help with his patient and Winston is hung up on his relationship with his brother.
400 20 "You Are the Blood" Debbie Allen Krista Vernoff May 26, 2022
The blood shortage at Grey Sloan Memorial continues. Meanwhile, Meredith makes a risky decision regarding a patient, and Owen's actions to help his fellow veterans come to light.



DVD Release



Cast Promotional Photos

TV Guide's Kate Walsh Return Photoshoot


  2. 2.0 2.1 ‘Grey’s Anatomy’ Renewed For Season 18 With Ellen Pompeo, Chandra Wilson & James Pickens Jr. Set To Return; ‘Station 19’ Picked Up For Season 5 By ABC
  3. Greg Germann Exits ‘Grey’s Anatomy’ As Series Regular