Grey's Anatomy Universe Wiki

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Grey's Anatomy Universe Wiki
Grey's Anatomy Universe Wiki
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Grey's Anatomy Seasons
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The show was officially renewed for a twenty-first season on April 2, 2024 for the 2024-25 broadcast season. It premiered on September 26, 2024 and airs on Thursday at 10/9c PM. The season will consist of 18 episodes.[1]

Summary

Plots

Cast

Main Cast

Special Guest Star

Recurring Guest Stars

Prominent Guest Stars

Recurring Co-Stars

Notes and Trivia

  • The show was officially renewed for season 21 on April 2, 2024.[2]
  • On May 13, 2024, it was announced that Jake Borelli would be leaving the series after season 20 with negotiations taking place for him to return for season 21 for a few episodes to wrap up Levi's storyline.[3]
  • On May 15, 2024, it was announced that Midori Francis is leaving the series as well, with negotiations taking place for her to return for a few episodes in season 21 to wrap up Mika's storyline.[4]
  • Furthermore, it was announced that as part of a cost-cutting move, several of the veteran series regular would face a reduction of their episodic guarantee (the number of episodic fees per season each series regular is entitled to per their contract), likely resulting in less appearances by said regulars throughout the season.[3]
  • Filming for the season presumably started on July 24, 2024. James Pickens, Jr. and Anthony Hill filmed together that day, as did Camilla Luddington and Chris Carmack. Jake Borelli shot his first scenes for the season that day as well, although other actors may have shot scenes on the days prior.[5][6][7]
  • On August 19, 2024, they were filming I Can See Clearly Now.[8]
  • The table read for This One's for the Girls took place on August 20, 2024.[9]

Episodes

No. in series No. in season Title[10] Directed by Written by Original air date[10]
431 1 "If Walls Could Talk" Debbie Allen Meg Marinis September 26, 2024
21x01-1
After firing some of Grey Sloan's best, Catherine continues to interfere with Meredith and Amelia's research. Accidents at a climate change protest bring unique cases to the hospital, and Bailey encounters a blast from the past.
432 2 "Take Me to Church" Kevin McKidd Michelle Lirtzman October 3, 2024
21x02-1
Meredith and Catherine continue to disagree, and Meredith confides in Bailey for support. Richard, Winston and Lucas spend the day outside of the hospital, and Blue deals with a relationship from his past. Levi meets the new hospital chaplain.
433 3 "I Can See Clearly Now" Victoria Mahoney Mark Driscoll October 10, 2024
21x03-1
Simone and Lucas work to balance their relationship while competing to assist on an awake kidney transplant. Teddy offers Amelia a new opportunity, and Ben's interview doesn't go as planned. Meredith's secret causes tension with Richard.
434 4 "This One's for the Girls" Debbie Allen Briana Belser October 17, 2024
21x04-1
Mika struggles with a life-altering personal matter. Meanwhile, Bailey and Ben navigate their personal and professional roles, while Levi finds a connection in an unlikely place. Jo and Link get surprising news.
435 5 "You Make My Heart Explode" Vanessa Parise Zoanne Clack October 24, 2024
21x05-1
During a high-stress day at Grey Sloan Memorial, the fates of a patient in critical condition and a helicopter-bound medical team hang in the balance. Teddy and Owen work on their marriage, while Bailey, Blue and Link treat a hospital employee.
436 6 "Night Moves" Bille Woodruff Jase Miles-Perez November 7, 2024
21x06-1
Teddy and Owen plan a date night that gets derailed in more ways than one, while Jo struggles to do it all at home. Mika adds more to her plate to make up for taking time off to be with her sister, and Levi is faced with a monumental decision.
437 7 "If You Leave" Allison Liddi-Brown Tameson Duffy November 14, 2024
21x07-1
The doctors at Grey Sloan must put aside their emotions under intense circumstances. Levi asks James a shocking question that could impact their future.
438 8 "Drop It Like It's Hot" Kevin McKidd Jess Righthand November 21, 2024
21x08-1
In the midst of a deadly heat wave, the team at Grey Sloan struggles to keep up with an overwhelming amount of patients. Amelia and Winston face a challenging surgery, while Jo and Lucas run an errand for the hospital that takes an unexpected turn.
439 9 "Hit the Floor"[11] Linda Klein[11] Jamie Denbo[11] March 6, 2025
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Spoilers


OldMer This page or section may contain spoilers about episodes that haven't yet aired in the US. OldC


  • Ellen Pompeo will appear in at least seven episodes and potentially as many as fourteen.[12]
  • Natalie Morales will appear in at least six episodes, with the possibility more will be added.[13]

Reception

Gallery

Cast Promotional Photos

Posters

Trailers


References

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