Grey's Anatomy Seasons
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17

The second season of Grey's Anatomy premiered September 25, 2005 and ended May 15, 2006. It was broadcast on ABC on Sunday nights at 10 PM, except for the two final episodes, which aired Monday, May 15, 2006, at 9 and 10 PM respectively. The first season had originally contained 14 episodes, but ABC decided to end the season early after 9 episodes. The 5 remaining episodes of season 1 were added to the 22 episodes ABC ordered for the second season, bringing season 2 to the total of 27 episodes, ending with a three-hour finale.


Life gets even more intense for the doctors and interns of Seattle Grace Hospital in year two as Meredith and Derek's relationship goes from odd to downright insane with the arrival of Derek's wife, and Alex lets his Izzie obsession out of the bag.


  • Cristina's ectopic pregnancy.
  • The love triangle with Meredith, Derek, and Addison.
  • Miranda Bailey's pregnancy.
  • Meredith sleeping with George.
  • George's relationship with Callie Torres.
  • Izzie and Alex's relationship.
  • Denny Duquette's crush on Izzie.
  • Cristina and Burke's relationship.


Main CastEdit

Special Guest StarsEdit

Recurring Guest StarsEdit

Prominent Guest StarsEdit

Recurring Co-StarsEdit

Notes and TriviaEdit

  • The first season was supposed to be 13 episodes, but ABC wanted the Grey's finale to air along with the Desperate Housewives finale. Rather than condensing or throwing out plot lines, the first season ended with the ninth episode the remaining four episode were saved the for the second season. Enough is Enough was created as the first new episode of the season, but aired as the second episode of the season. Bring the Pain, which aired as the series' 14th episode, has been cited in series creator Shonda Rhimes' blog as having been originally intended as the first season finale.
  • The series' opening credit sequence was also dropped by the last half of the second season, replaced by a title card displayed at the end of the first act and credits displayed over the opening of the second act of each episode.
  • Most of the episode voice overs are narrated by Meredith Grey, but there are three exceptions:
  • Chandra Wilson was pregnant with her son during part of the season, like her character.
  • All main characters of the season appear in every episode, except for Miranda Bailey, who's absent for one episode.



DVD ReleaseEdit


The "Grey's Anatomy: The Complete Second Season – Uncut" boxset was released in region 1 on September 12, 2006. On May 28 and January 10, 2007, the DVD was released in regions 2 and 4 respectively.

Set DetailsEdit

The region 1 boxset contains the 27 episodes of the season, with four extended. The DVD box contains 6 discs. Other set details are:

  • English (Dolby Digital 5.1 Surround)
  • 1.78:1 aspect ratio
  • Subtitles: English, French, and Spanish

In the UK, the DVD set only contains the last 22 episodes of the season, as the first 5 were included in the season 1 DVD set.

Special FeaturesEdit

Additional to the episodes, the season 2 DVD set also contains a couple of special features:


Cast Promotional PhotosEdit